The depth of the San Francisco 49ers, especially on defense, is insanely thin. They cannot afford to have a few players or more on that side of the ball out. U

Learn which TV channel or how to live stream the NFL Week 15 San Francisco 49ers and Tennessee Titans game, Sunday, Dec. 14.

San Francisco 49ers quarterback Brock Purdy has a 4–1 record as a starter this year, despite battling a turf toe injury he suffered at the very start of the season.

Preview the Week 15 matchup between the San Francisco 49ers and Tennessee Titans with predictions, odds, over/under, spread, betting lines and more.

The San Francisco 49ers have needed someone to step up on the edge, and luckily, one of their free-agent signings has worked out better than expected.

San Francisco coach Kyle Shanahan explained how his defense plans to slow down Tennessee Titans QB Cam Ward during an interview on "49ers Game Plan."

Now the 49ers are on the upswing and the Eagles look as if they’re lost again. They lead the NFC East, but have gone from 8-2 to 8-5, giving up 575 yards in the three losses. Hurts is spewing turnovers, and had two on one play (an interception and a lost fumble) on the same play in a 22-19 overtime loss to the Los Angeles Chargers.

The San Francisco 49ers should beat the Tennessee Titans with relative ease in Week 15. If the passing offense does not have a massive game, it will be a bit co