Former Wisconsin Badgers running back Isaac Guerendo is in line to serve as the San Francisco 49ers starting running back for ...

The 49ers claimed former Jets RB Israel Abanikanda, and re-signed WR Ronnie Bell and RB Ke’Shawn Vaughn to the practice squad ...

The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly ...

Star pass-catcher George Kittle and the San Francisco 49ers play the Buffalo Bills on Sunday at 8:20 p.m. ET at Highmark ...

Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling ...

San Francisco 49ers star running back Christian McCaffrey will not need surgery on his injured right knee but will miss the ...

The Buffalo Bills and San Francisco 49ers will each be without critical contributors for their Week 13 primetime clash.

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian ...

Buffalo (9-2) brings a six-game winning streak into a matchup with San Francisco (5-6) on Sunday, December 1, 2024 at ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...

The Buffalo Bills (9-2) will try to build on a six-game winning streak when they host the San Francisco 49ers (5-6) on Sunday ...

San Francisco 49ers running back Christian McCaffrey will not need surgery on his injured right knee but he will miss the ...