The "replication crisis" refers to a problem in the sciences where findings from previous experiments don't hold up when studies are repeated. It is a particular issue for those in the behavioral ...

Ideally, specific treatment for a cancer patient is decided by a multidisciplinary tumor board, integrating prior clinical experience, published data, and patient-specific factors to develop a ...

Many antineoplastics are designed to target upregulated genes, but quantifying upregulation in a single patient sample requires an appropriate set of samples for comparison. In cancer, the most ...

Bayesian trials formally integrate prior evidence with accruing data to yield posterior probabilities, supporting interim learning, adaptive modifications, and direct predictive futility/efficacy ...