Fifty-three individuals previously characterized 10, 11 were enrolled in this study. Samples were grouped considering four genotypes: (a) CF patients homozygous for p.Phe508del (CF-F508del), n=7; (b) ...
The cystic fibrosis transmembrane conductance regulator (CFTR) is a complex protein that helps maintain fluid balance in several organs. Mutations in the CFTR protein can lead to symptoms of cystic ...