The kinetochore is a complex molecular machine that directs chromosome segregation during mitosis. It is one of the most elaborate subcellular protein structures in eukaryotes, comprising more than ...

Centromeres are curious structures. These specially organized chromosomal regions are best known for their unique and critical role in cell division, in which they are well understood to serve as the ...

Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in ...

An international research team has achieved a significant breakthrough in research into the reproduction of dogrose. The study, which has now been published in Nature, shows how differences in the ...

This is a preview. Log in through your library . Abstract Replicated sister chromatids are held together until mitosis by cohesin, a conserved multisubunit complex comprised of Smc1, Smc3, Sccl, and ...

Just like you might use a belt to keep your clothes in place, the centromere holds a pair of chromatids together and attaches it to the mitotic spindle during cell division to ensure that each ...

Researchers at Osaka University say they have clarified the structure of the centromeric region in chicken cells using cryogenic electron microscopy (cryo-EM). The team published its study in “The ...

The centromere of chromosomes plays a crucial role in cell division. Using the model plant Arabidopsis thaliana, an international team of researchers has investigated how two crucial proteins -- KNL2 ...

A joint research group team led by Sayuri Tsukahara and Tetsuji Kakutani of the University of Tokyo has clarified a mechanism of how retrotransposons, genetic elements that can "jump around" ...

Sister chromatid cohesion is essential to maintain stable connections between homologues and sister chromatids during meiosis and to establish correct centromere orientation patterns on the meiosis I ...

Researchers from the Max Planck Institute have elucidated the molecular mechanism regulating the replenishment of centromeric protein A (CENP-A) at the centromere. The study reveals how Polo-like ...