Noninvasive prenatal testing (NIPT), which relies on cell-free fetal DNA in the mother's blood, is increasingly common. Yet two studies published online Apri 1 in the New England Journal of Medicine ...

New research shows genome duplication in the ancestor of modern gymnosperms, a group of seed plants that includes cypresses and pines, might have directly contributed to the origin of the group over ...

This distinction represents a key difference between the functions of the leading strand clamp loader (CTF18-RFC) and the lagging strand clamp loader (RFC) and illuminates an important aspect of ...

Researchers at USC have developed a yeast model to study a gene mutation that disrupts the duplication of DNA, causing massive damage to a cell's chromosomes, while somehow allowing the cell to ...

A new study shows that how a cell fails to divide after copying its DNA can determine its fate. Cell division is one of the most fundamental and complex processes underpinning life. In human cells, ...

A cell copies all of its DNA, gears up to split in two, and then just… doesn’t. It sits there, swollen with a double genome, and nobody notices. This kind of silent failure has been observed in labs ...

DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells use ...