New research has identified the pain pathways between the gut and brain Researchers have identified the nerve pathways responsible for pain signals from the bowel to the brain, paving the way for new ...

Salk scientists uncover a key neural circuit in mice that gives pain its emotional punch, opening new doors for treating fibromyalgia, migraine, and PTSD LA JOLLA (July 9, 2025)—Pain isn’t just a ...

"By pinpointing these pathways, we now know how signals from the gut are being transferred and processed in the nervous system appropriately, giving us a clear guide of what neural pathways to target ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

A new editorial paper titled "Decoding the mechanism behind MCL-1 inhibitors: A pathway to understanding MCL-1 protein stability" has been published in Oncotarget. In this new editorial, researchers ...

Deep in our cells, a wide range of processes are occurring constantly. These cellular processes rely on enzymes to act as catalysts and set off a series of molecular interactions. There are still many ...

Empathy—the ability to share and understand the emotions of others—is a cornerstone of human social interactions. When we witness someone in pain, we often experience a mirrored emotional response, a ...

Pain in sickle cell disease is frequently misunderstood, leading to mistrust between patients and providers. Many patients report managing their pain crises at home, because they fear being dismissed, ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...