In December 1981, Manuel Göttsching was due to fly from his native Berlin to Hamburg. In need of some music for his Walkman, he decided to record an idea that he was working on. Thirty-two years later ...

The restlessly innovative German guitarist went on to make records including the legendary E2-E4, a foundational source for techno and ambient house Although it might help, there’s a fair chance you ...

Apolipoprotein E (apoE) is an essential component of lipoprotein particles in both the brain and periphery, and exists in three isoforms in the human population: E2, E3, and E4. ApoE has numerous, ...

Mention ApoE and Alzheimer’s, and the conversation turns to the E4 allele, the strongest susceptibility gene for the disease. But ApoE has another side, in ApoE2. Though this isoform protects against ...

As the strongest risk factor for Alzheimer’s disease, ApoE4 has a bad reputation, and rightly so. Yet shade thrown on ApoE4 may be obscuring the inconvenient truth that ApoE3 isn’t so innocent, either ...

The APOE gene—coding for a protein involved in lipid transport and implicated in the clearance of amyloid-beta, one of the proteins that builds up in the brain in Alzheimer's disease—exists in three ...

Of the many moments where the old analogue format of the rock aristocracy mutated into the new electronic style surging across international club dancefloors, 1989’s 'Sueño Latino' by the Italo house ...