Bacterial protein glycosylation systems encompass a diverse array of enzymatic mechanisms responsible for the covalent attachment of carbohydrate moieties to proteins. These modifications, which ...

Aberrant Glycosylation Drives Kidney Disease Pathogenesis. This schematic illustrates how abnormal glycosylation contributes to diverse kidney diseases: (A) galactose-deficient IgA1 in ...

Scientists from Croatia have identified 90 genes associated with the glycosylation of immunoglobulin (IgG). The team, who has already shown that 20 of these genes can be used to tweak glycosylation ...

A comprehensive study mapped the dynamic glycosylation landscape of rat serum proteins, uncovering sex- and time-dependent variations with clear cell-type specificity. Researchers found distinct ...

Kidney diseases affect nearly 700 million people worldwide and are a growing cause of mortality and health care costs. Chronic kidney disease (CKD) alone contributes to over 1.2 million deaths ...

Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to our physiology—in health and disease. A new study from EMBL Heidelberg ...

Using a new method to study how carbohydrates modify proteins, scientists have discovered that gut bacteria can alter molecular signatures in the brain. Our guts are home to trillions of bacteria, and ...

The main text details the experimental design, including the generation of CO and CPO ADAMTS13 variants using different algorithms, and the evaluation of these variants in terms of protein expression, ...

The microbes in the human gastrointestinal tract can have a significant influence on human health and disease, and this gut microbiome has been associated with a wide array of characteristics and ...