Three years after a team of Caltech scientists showed that pairs of entangled photons could double the resolution of a light ...

Light microscopy is a key tool that scientists use to image cells, organelles, subcellular structures, and molecules such as proteins and nucleic acids. Because visible light leaves biological ...

When designing microscopes, optical engineers have long faced a trade-off between speed, field of view and resolution. But improving one of these properties typically comes at the expense of another.

With a new microscope that's as light as a penny, researchers can now observe broad swaths of the brain in action as mice move about and interact with their environments. As a mouse explores its ...

Hosts of new applications have turned the light microscope into an exquisitely sensitive measuring device that can be used to image dynamic cellular events right down to the molecular level. Indeed, ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...

Neural activity is three-dimensional and fast. Signals propagate through brain circuits on millisecond-to-microsecond ...

What is the Diffraction Limit? The diffraction limit is a fundamental barrier in optical microscopy that sets the minimum size of features that can be resolved using conventional light microscopes. It ...