“It means he most likely will,” coach Kyle Shanahan said of Jones starting, via David Bonilla of 49erswebzone.com. “We’ll see how Brock does tomorrow. But yeah, Mac’s much better than he was last week, and Brock is doing better than he did last week.”

Ricky Pearsall was once again a DNP as he continues to recover from a knee injury. Pearsall wasn’t the only receiver who didn’t practice. Marquez Valdes-Scantling was a new addition to the injury report. He has a calf injury. Per Matt Maiocco, Valdes-Scantling will miss a couple of weeks.

Schefter: 49ers’ Jones, Jennings expected to play vs. Bucs; Pearsall, Purdy updates “Jones has been managing knee and oblique injuries, while Jennings has been recovering from ankle and rib issues. Their availability gives the 49ers’ offense a much-needed boost as they look to improve on their 4-1 record.”

The 49ers’ inactives are Purdy (toe), Pearsall (knee), wide receiver Jordan Watkins (calf), defensive lineman Yetur Gross-Matos (hamstring), linebacker Nick Martin and running back Jordan James.

After Sunday's game, Jones said playing through injuries is in the team's DNA. But you have to wonder how long that DNA is sustainable.

The 49ers are to have both wide receiver Jauan Jennings and quarterback Mac Jones on the field against the Buccaneers in Week 6.

The 49ers (4-2) lost Fred Warner to a first-quarter ankle injury and went on to lose 30-19 to the host Tampa Bay Buccaneers.

The San Francisco 49ers entered 2025 battling the same demon that haunted them last season, injuries. A year after the injury bug derailed their campaign, the Niners have somehow managed to grind through the setbacks and sit at 4-2 after six games.