Proteins that respond to external stimuli function as molecular switches, playing a vital role in the precise regulation of biological processes. Therefore, if protein switches could be artificially ...
Researchers at the University of Bayreuth and Forschungszentrum Jülich have demonstrated that specific light-sensitive enzymes—so-called sensor histidine kinases (SHKs)—transmit their signal through a ...
A mechanism that could help scientists harness enzymes for use in drug discovery has been discovered in a research breakthrough at the University of Birmingham. In a study published in Science ...
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Bacterial energy enzyme reveals dual-trigger sodium pump mechanism, offering antibiotic clues
The Na +-NQR enzyme is vital for energy production in pathogenic bacteria like the one that causes cholera, making it a highly promising target for new antibiotics. Researchers combined modified ...
A new method that successfully designs serine hydrolase enzymes capable of catalyzing ester hydrolysis with high efficiency, demonstrates a computational approach for creating de novo enzymes that ...
Announcing a new publication for Acta Materia Medica journal. Monoamine oxidase (MAO) is a useful target in the treatment of neurodegenerative diseases and depressive disorders. Understanding the ...
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