Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA). This condition can cause symptoms including muscle weakness, ...

First-of-its-kind therapy developed by Johns Hopkins researchers cleared for treatment of Barth syndrome, a condition that ...

Using sequencing techniques, researchers associated 51 mutations in mitochondrial DNA with amyotrophic lateral sclerosis (ALS), an incurable degenerative neurological disorder that leads to muscle ...

Researchers at Leiden University in the Netherlands developed kidney organoids derived from patient stem cells to examine the ...

Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental ...

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these mutations cause serious diseases that pass down only through mothers. They ...

Prince Frederik of Luxembourg died from a genetic disease called PolG, but experts hope his passing could bring more awareness to the rare condition that impacted his life. Prince Frederik, 22, died ...

The CRISPR gene editing tool has been revolionary for the research lab, and it has also been used to transform the lives of a handful of patients of a few genetic diseases. Now scientists have used ...

The discovery centers on the unique strands of DNA contained within our mitochondria, the power stations of our cells. By banishing their 'mtDNA' into the surrounding cytoplasm, mitochondria can cause ...