We can all recognise that feeling of muscle fatigue after taking a brisk walk, cycling, running or playing football. Our ability to engage in physical activity for long periods of time is thanks to ...

This Collection supports and amplifies research related to SDG 3 and SDG 9. Mitochondrial dysfunction has been identified as a hallmark of aging, playing a central role in age-associated decline ...

Scientists at Walter and Elizabeth Hall Institute (WEHI) have made what they describe as a huge leap forward in the fight against Parkinson’s disease, solving a decades-long mystery by determining the ...

Longevity science has spent decades chasing single molecules that might slow aging, but most candidates have delivered modest, inconsistent results. A new line of research is now pointing to a ...

Mitochondria organelles came from primordial bacterial endosymbionts and still preserve distinct genes for important functions like making ATP. To speed the emerging therapeutic research into the ...

Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear. Research published in the Biophysical Journal shows that ...

Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.

I always wanted to understand life. What moves us? What allows us to heal and thrive? And what goes wrong when we get sick or when we eventually stop breathing and die? My search for answers to these ...

Researchers have developed experimental drugs that encourage the mitochondria in our cells to work a little harder and burn more calories. The findings could open the door to new treatments for ...