Coming into the 2024 NFL season, it certainly looked as if the Buffalo Bills were in for a reality check. From 2019 through 2023, the Bills had a regular-season record of 58-24-0, and that win total,

It's hard to argue against Cowherd at this point. Buffalo has been able to not only defeat the Chiefs in the regular season but remain a favorite to become the conference's top seed for the first time since 1993.

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been tabbed a potential Super Bowl preview. Only one of the prime-time foes looked the part,

As the Bills head toward the 2024 NFL playoffs, the team's nightmare playoff matchup would be a rematch with Derrick Henry and the Ravens.

SportsLine's model has simulated San Francisco vs. Buffalo on Sunday Night Football 10,000 times and revealed its SNF picks and NFL predictions

The Bills and the San Francisco 49ers went head-to-head in freezing conditions Sunday, with Bills fans and staff digging out snow.

The San Francisco 49ers make the trip to snowy Buffalo, NY to face Josh Allen and the Buffalo Bills on Sunday Night Football.

Buffalo Bills quarterback Josh Allen was stellar in his team's Week 13 win over the San Francisco 49ers, and NFL MVP odds have, thus, responded.

The Buffalo Bills are on a fast track to win the AFC East championship and clinch a playoff spot. But that won't happen in Week 12 of the NFL season. After beating the reigning Super Bowl champions Sunday, the Bills are at 9-2. The last time the team had ...

San Francisco was without starting quarterback Brock Purdy (shoulder) last week, but he is expected to return in time for a Sunday Night Football matchup against the Buffalo Bills during the Week 13 NFL schedule. While Purdy is officially listed as ...