Anyone who studied a little genetics in high school has heard of adenine, thymine, guanine and cytosine -- the A, T, G and C that make up the DNA code. But those are not the whole story. The rise of ...

Human Rho GTPases (of which there are 22 members) comprise a main branch of the Ras superfamily of small GTPases and GDP/GTP-regulated molecular switches. Rho GTPases are activated by the direct ...

Nucleotides are essential components of a wide range of cellular processes; therefore, the maintenance of these levels through various metabolic pathways is crucial for adequate cellular function. The ...

Cystic fibrosis, sickle cell anemia, Huntington's disease and phenylketonuria are all examples of disorders caused by the mutation of a single nucleotide, a building block of DNA. The human DNA ...