C&EN

Crystal structures of the novel coronavirus protease guide drug development

With the novel coronavirus, SARS-CoV-2, spreading across the globe, labs are shutting down as people are told to stay at home. But some labs are still hard at work, looking for druggable targets to ...
Medscape

Protease Inhibitors Increase Small-For-Gestational-Age But Not Other Pregnancy Risks

Pregnant women with HIV can be reassured that protease inhibitors are safer than previously thought in terms of risk to the foetus, according to research from the National Perinatal Epidemiology Unit ...
Business Wire

Enanta Pharmaceuticals Announces Positive Data from a Phase 1 Clinical Study of EDP-235, its Oral 3CL Protease Inhibitor Designed for the Treatment of COVID-19

WATERTOWN, Mass.--(BUSINESS WIRE)--Enanta Pharmaceuticals, Inc. (NASDAQ: ENTA), a clinical-stage biotechnology company dedicated to creating novel, small molecule drugs for viral infections and liver ...
Business Wire

Seismic Therapeutic Doses First Cohort in Phase 1 Clinical Trial of S‑1117, a Novel Pan‑IgG Protease Therapy for Antibody-Mediated Diseases

WATERTOWN, Mass.--(BUSINESS WIRE)--Seismic Therapeutic, Inc., the machine learning immunology company, today announced the dosing of the first healthy subject cohort in a Phase 1 clinical trial of ...