An error in protein conformation can lead to disease. What are the genetic and molecular causes for incorrectly formed proteins? molecules. In 1917 the German chemist ...

Prion diseases, Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis (ALS) are all part of the landscape of neurodegenerative diseases linked to protein ...

From the story behind the name of Yumanity Therapeutics to the science of protein misfolding, former Onyx Pharmaceuticals CEO Tony Coles talks about his new venture. Over the past five years or so, ...

Proteins misfolding and clumping together, a process known as aggregation, is a key feature seen in several neurological conditions, including Alzheimer's and Parkinson's diseases. These disorders ...

TORONTO--(BUSINESS WIRE)--Paradox Immunotherapeutics (“Paradox”), a pharmaceutical company focused on the development of innovative antibody therapies that treat protein misfolding diseases, today ...

AMES, Iowa – Iowa State University researchers have described with single-molecule precision how copper ions cause prion proteins to misfold and seed the misfolding and clumping of nearby prion ...

The brain of a rat in which a fluorescent protein has been used to highlight transplanted human brain cells - Copyright Stanford University/AFP Sergiu PASCA The brain ...

Misfolding occurs when a protein adopts a conformation which differs from the native one. The researchers, funded by the National Institute of Neurological Disorders and Stroke, have developed an ...

The first synthetic fragment of tau protein has been created, revealing more about the diagnosis and treatment of neurodegenerative diseases. Researchers at Northwestern University (IL, USA) and the ...

An interdisciplinary team led by School of Engineering and Applied Science’s Lee C. Bassett and Dani Bassett, also of the School of Arts & Sciences, have studied the mechanical properties of prions, ...

New computer simulations that model every atom of a protein as it folds into its final three-dimensional form support the existence of a recently identified type of protein misfolding. Proteins must ...