SSEmb: A joint embedding of protein sequence and structure enables robust variant effect predictions
The ability to predict how amino acid changes affect proteins has a wide range of applications including in disease variant classification and protein engineering. Many existing methods focus on ...
High-accuracy protein complex structure modeling based on sequence-derived structure complementarity
In living organisms, proteins perform key functions required for life activities by interacting to form complexes. Determining the protein complex structure is crucial for understanding and mastering ...
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