A collaboration between 34 researchers at 18 institutions has looked into the efficacy and safety of psilocybin in patients with major depressive disorder. A randomized, double-blind, ...

Psilocybin, magic mushrooms, shrooms–whatever you call it, the fruiting bodies have been making waves. From legalization and decriminalization in states like Oregon to exciting studies on the ...

Penn researchers found that psilocybin can calm brain circuits tied to pain and mood, easing both physical suffering and emotional distress in animal studies. The compound works in the anterior ...

One of the biggest questions in the psilocybin world is, “How much do you take?” The answer will inevitably vary in each individual situation. This excerpt from the new book Welcome to Psilocybin by ...

A single high dose of psilocybin results in dramatic, acute, and persistent changes to the brain's functional networks in healthy adults, results of a small randomized controlled trial show. The new ...

A single dose of the psychedelic compound psilocybin could be enough to remodel connections of specific brain networks, which may explain how the drug helps to treat some mental health conditions.

High-dose psilocybin is associated with greater relief from depressive symptoms than placebo or escitalopram, with no increased risk for severe adverse events, a new meta-analysis suggests. Placebo ...

Harm caused by repeated concussions, especially in the context of sports, has gained attention in both research and the media. A new study has found that psilocybin, the psychedelic ingredient in ...

High doses of psilocybin - the active ingredient in magic mushrooms - appears to have a similar effect on depressive symptoms as the selective serotonin reuptake inhibitor (SSRI) drug escitalopram, ...