Atherosclerosis has long been framed as a plumbing problem: cholesterol builds up, inflammation smolders, and arteries stiffen until heart attacks or strokes follow. Statins transformed this picture ...

RUDN University scientists have discovered that in weightlessness, the contractile activity of smooth muscles in the hollow organs of the gastrointestinal tract is disrupted. New data must be taken ...

The foreign body response is a clinically relevant process that can lead to issues with biocompatibility in implanted medical devices due to fibrosis. While the inflammatory nature of the foreign body ...

Using gene editing in a preclinical model, researchers at UT Southwestern Medical Center blocked the symptoms of a rare smooth muscle disease before they developed. Their findings, published in ...

A new study shows targeting a protein in smooth muscle cells can block and decrease buildup of atherosclerotic plaque in mouse models, according to researchers. A new study shows targeting a protein ...

The mechanical environment of smooth muscle cells and the surrounding extracellular matrix orchestrates vascular tone, tissue remodelling and pathology. Smooth muscle cells reside within a fibrous ...

Using whole genome sequencing, researchers identified a single variant in a microRNA gene, MIR145-5p, as the source of multisystemic smooth muscle dysfunction syndrome, which had gone undiagnosed in a ...

The human aortic wall is composed of three layers and different cell types: the intima, media and adventitia composed of endothelial cells, vascular smooth muscle cells (VSCMs), fibroblasts, ...

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