Optical genome mapping: hidden structural variants in families with inherited retinal diseases Kornelia Neveling1,3, Zeinab Fadaie1,2, Suzanne de Bruijn1,2, Tuomo Mantere1, Ronny Derks1, Lonneke ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene activity—across 39 human cell types, revealing a complex landscape of ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

An illustration of multicolored tangle of threads within a small black sphere. A 3D illustration shows DNA packaged into the nucleus, scientists with the 4D Nucleome project are now building accurate ...

Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer. DNA is well-known for its double helix shape. But the human genome ...

The human genome is no longer just a sequence to be read. It’s a dynamic structure that twists, folds, and reshapes itself in ways that help determine how life functions at the cellular level. In a ...

It’s called a pangenome, and it could explain the DNA that makes each of us unique. The joke about the Human Genome Project is how many times it’s been finished, but not actually. The first time was ...

The innovation was made by researchers from Northwestern University, and the study was published in Nature. Researchers are now using AI and 4D genome to see how DNA folds and moves in genetic ...

Researchers have conducted the most comprehensive analysis to date linking plasma proteins to genetic variation in individuals from continental Africa. Their study addresses a long-standing gap by ...