Much of the persistent confusion about the cellular actions of digitalis may be attributed to three factors. First of all, digitalis and related cardio-active steroids exert their therapeutic actions ...

OUR knowledge of the action of digitalis on the heart was fouded by William Withering, of Birmingham, whose classical treatise was published in 1785. Since that time, owing to the multiplicity and ...

FOR almost two hundred years digitalis has been so essential and effective in cardiac therapy that it has been called the most useful drug of all times. Despite widespread and skillful clinical use ...