The Cardinals were "discombobulated" on the offensive end against the Razorbacks, and didn't have a physical edge on the defensive side.

Arkansas head coach John Calipari addressed the Razorback fanbase after beating Louisville, calling out a disrespectful “overrated” chant.

Louisville head coach Pat Kelsey was agitated with the Cardinals after their Wednesday night loss to Arkansas.

LOUISVILLE, Ky. - The Louisville men's basketball program has run into their first true adversity of the you 2025-26 season. Tasked with facing Arkansas in Fayetteville for their leg of the ACC/SEC Challenge, the Cardinals could not come out of Bud Walton Arena with a win, dropping the ranked showdown 89-80 on Wednesday night.

FAYETTEVILLE, Ark. (AP) — Trevon Brazile scored 21 points to lead five Arkansas players in double figures as the 25th-ranked Razorbacks built a big lead and held off No. 6 Louisville 89-80 on Wednesday night.

The Louisville Cardinals tip off against the Arkansas Razorbacks at 7:15 p.m. ET Wednesday at Bud Walton Arena in Fayetteville, Arkansas.

No. 6 Louisville men’s basketball picks up its first loss of the season at No. 25 Arkansas 89-80, in a game where Pat Kelsey’s Cards didn’t lead once. The Cardinals played catch-up over the course of the evening,

The Arkansas Razorbacks are hosting the Louisville Cardinals in the ACC-SEC Challenge. Here are live updates from Bud Walton Arena.