This article was originally published on Psychedelic Spotlight and appears here with permission. New study suggests that a non-hallucinogenic LSD analog may hold therapeutic potential for mood ...

Scientists have identified a drug that appears to produce the antidepressant effects of LSD without the psychedelic side effects — at least in mice.

Researchers have developed a groundbreaking version of LSD that retains the drug's brain-healing benefits without the mind-altering effects.

LSD blotter tabs sit on top of a US quarter coin. A drug based off of psychedelic LSD appears to relieve depression and anxiety in mice, but without the hallucinogenic side effects.

A team of scientists in California has tweaked the hallucinogenic drug LSD to make it usable to treat schizophrenia and other neuropsychiatric and neurodegenerative diseases. According to the ...

What if you could use medical LSD to treat schizophrenia and other disorders? Well, new research may have found a way.

LSD is thought to induce its prototypical psychedelic effects primarily via stimulation of the serotonin 5-HT2A receptor.

LSD was first synthesized by Swiss chemist Albert Hofmann in 1938, working for Sandoz Pharmaceuticals (now part of Novartis) in Basel, Switzerland. He discovered its powerful psychoactive effects ...

NPR science podcast Short Wave brings us the stories of how Fiddler crabs drum their mating songs into the sand, growing chicken nuggets in the lab, and a drug like LSD -- without the trip.

But they have other impacts, too - mind-bending side effects, for one. NPR's Jon Hamilton reports on a drug based on LSD that appears to treat depression in mice without taking the animals on a trip.