Figure 1: Schematic diagram of the HIV–1 p66–p51 heterodimer (Ren et al. 4). Figure 2: Schematic diagram of the HIV–1 RT heterodimer in complex with double–stranded DNA (adapted from ref.

When we know the structure of a protein, we can attempt to design small drug molecules to bind to it and block its function. The power of this approach has been shown in the battle against HIV and ...