Star running back Christian McCaffrey will miss the remainder of the regular season with a PCL injury sustained in the San ...

The San Francisco 49ers were hit by another family tragedy with the announcement that star left tackle Trent Williams’ wife ...

Micah Roberts, on a 25-6 run on San Francisco 49ers picks, has revealed his Sunday Night Football expert picks for San ...

The tragedy of this 49ers’ season epitomized. For the first time since returning to the lineup in Week 10, McCaffrey looked ...

Lake-effect snow has been hitting Buffalo throughout the holiday weekend with is expected to continue off and on through ...

For as disjointed and dry as the 49ers are offensively, it's their run defense that has crushed their chances and led to road ...

Now, looking ahead to Week 14, the 49ers will return home for a matchup with 2024 No. 1 overall pick Caleb Williams and the ...

The Buffalo Bills secured their fifth consecutive AFC East title by dominating the San Francisco 49erss 35-10 in severe ...

The Bills are coming off a bye week and riding a six-game winning streak behind MVP favorite Josh Allen, most recently ...

Meanwhile, Harbaugh is in Los Angeles, coaching the Chargers to a 7-3 record, with quarterback Justin Herbert looking like a ...

Two Green Bay Packers starters, cornerback Jaire Alexander and linebacker Edgerrin Cooper, did not practice on Friday and ...

That’s all you can call the Niners’ loss to the Packers on Sunday. Any glimmer of hope was short-lived or quickly sabotaged. Any positive play was rapidly undercut. The Niners’ opponents ...