The 49ers scored on their first five possessions and seven of eight in the game, with only a fumble marring their streak.

Although Brock Prudy and the San Francisco 49ers have dealt with many health issues throughout the season, they still find ...

The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the team’s fourth win in a row.

San Francisco 49ers QB Brock Purdy's quick throw to TE George Kittle resulted in a 24-yard gain in the team's Week 15 matchup.

The Tennessee Titans aim for their third road victory of the season with a trip to the San Francisco 49ers on Dec. 14 in ...

San Francisco 49ers RB Christian McCaffrey capped the drive with a one-yard rushing touchdown against the Tennessee Titans.

San Francisco 49ers running back Christian McCaffrey rushes for a 1-yard touchdown against the Tennessee Titans.

SANTA CLARA, Calif. — Brock Purdy threw three touchdown passes and the San Francisco 49ers started the stretch run of their ...

The 49ers are dominating the Titans, as they should, with a 14-3 lead early in the second quarter. Christian McCaffrey scored ...

SANTA CLARA — Christian McCaffrey will continue his two-pronged assault on a 49ers’ playoff berth as well as his quest to ...

The Tennessee Titans visit the San Francisco 49ers at Levi's Stadium. Here are injury updates on Christian McCaffrey and the ...

For the first time this year, Christian McCaffrey is questionable. While no one is ever rooting for an injury, CMC's back issues could be the shining light in t ...