Christian McCaffrey's injury against the Bills could be due to the heavy workload he received since returning to the 49ers.

The San Francisco 49ers are moving forward without star running back Christian McCaffrey or backup Jordan Mason for the ...

During a segment of "Good Morning Football", NFL Network Insider Ian Rapoport elaborates on the severity of the injury report ...

NFL Network's Akbar Gbajabiamila shares the NFL Way to Play Week 13 winners. NFL Network's Kyle Brandt crowns Week 13 angry ...

49ers head coach Kyle Shanahan told reporters Monday that McCaffrey suffered a posterior cruciate ligament (PCL) injury ...

The Thanksgiving holiday was make or break for a lot of teams in the NFL. Some teams separated themselves with respect to ...

NFL Week 14 waiver wire cheat sheet for all league sizes and formats, with players you need to add, drop and stream in your ...

The 49ers have lost three games in a row, but their season isn't dead yet. Sure, they're in last place in the NFC West, but ...

The San Francisco 49ers and fantasy football players who were relying on the NFC West team's running backs are probably all ...

The 2024 season has been a renaissance for running backs. After years of toiling away on middling teams, Philadelphia Eagles ...

The San Francisco 49ers' brutal battle against the injury bug continues to get worse, as they have lost their two main running backs — Christian ...

San Francisco picked up running back Israel Abanikanda off waivers from the Jets after a slew of injuries in their backfield.