San Francisco 49ers running back Isaac Guerendo discussed being the "next man up" with Christian McCaffrey and Jordan Mason expected to miss significant time due to injury.

On Tuesday morning's PFT Live, I threw out the idea of the Bears ditching the normal approach to hiring head coaches and calling the 49ers to see whether they'd be willing to trade Kyle Shanahan.

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

ProFootballTalk founder Mike Florio has an intriguing idea for a change of scenery for Kyle Shanahan. Appearing on “The Rich ...

McCaffrey immediately checked himself out of the game and ran right into the medical tent. The 49ers star RB missed the ...

The San Francisco 49ers officially placed Christian McCaffrey on Injured Reserve on Tuesday. McCaffrey's 2024 season is done ...

There are plenty of names on any list of Chicago Bears head coaching candidates, but should the team explore a trade for a ...

McCaffrey was initially said to be out at least six weeks — with five weeks left in the season. Niners head coach Kyle ...

San Francisco 49ers wide receiver Jauan Jennings hasn't been available to the media recently, leaving reporters wondering why ...

Head coach Kyle Shanahan reflected on the team's performance against the Bills, previewed the upcoming Week 14 matchup ...

Nick Bosa is one of several San Francisco 49ers players who will not participate in practice on Wednesday as the team begins ...