There are no teams on bye around the NFL in Week 13, which means we'll be treated to a packed slate of Sunday games even ...

They don't get a divisional opponent in Week 13, but a struggling San Francisco 49ers team still possesses plenty of firepower for Buffalo to be concerned with as it starts December. Here are five ...

Without Bosa, the 49ers lack any real elite threat in the trenches which could be a major issue against Buffalo’s solid ...

Josh Allen is currently the frontrunner in NFL MVP odds, and we expect the Bills superstar quarterback to use his athleticism ...

49ers HC Criticized for Late-Game Management One word that Lynch uses in his above quote is “finishing.” That coincides with ...

The Bills are currently scheduled to host the San Francisco 49ers on Sunday Night Football at 8:20 p.m. ET. "Whiteout ...

Running back Christian McCaffrey says the San Francisco 49ers are “hungry” to make a playoff push even with the defending NFC ...

Heads have already started to roll at the San Francisco 49ers. Entering the final third of the regular season, management ...

Preview the Week 13 matchup between the Buffalo Bills and San Francisco 49ers with predictions, odds, over/under, spread, ...

Buffalo Bills offensive stars prepare to shine against the San Francisco 49ers' struggling defense in a critical AFC-NFC ...

It's Week 13, and the San Francisco 49ers are at 5-6 in the season. The team travels to Buffalo to take on the leaders of the ...

SportsLine's advanced model has locked in its Week 13 NFL betting picks and football predictions from 10,000 simulations to ...