San Francisco 49ers coach Kyle Shanahan is sharing an update on Trent Williams and his family after the left tackle's son was ...

The San Francisco 49ers are a gigantic mess. Nothing looks right on offense. Injuries have decimated both sides of the ball.

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

San Francisco 49ers running back Christian McCaffrey was placed on injured reserve for the second time this season after ...

McCaffrey should be fine long term, though it's hard to say whether he'd be able to play again this season if the 49ers made ...

San Francisco 49ers DB Deommodore Lenoir is showcasing his support for athletes with Down syndrome through custom-designed ...

San Francisco 49ers linebacker Fred Warner recently revealed that he has been playing through a bone fracture in his ankle, ...

ProFootballTalk founder Mike Florio has an intriguing idea for a change of scenery for Kyle Shanahan. Appearing on “The Rich ...

The 49ers superstar made the statement in a lengthy caption on his Instagram fee after the team put him on injured reserve ...

On Sunday night against the Buffalo Bills, star running back Christian McCaffrey suffered a knee injury that may cost him the ...

Josh Allen and the Buffalo Bills put on a show in the snow during "Sunday Night Football" in Week 13, besting the San ...

Could the San Francisco 49ers trade head coach Kyle Shanahan? One insider thinks so. The post 49ers Trade Proposal Sends Kyle ...