Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

The San Francisco 49ers are a gigantic mess. Nothing looks right on offense. Injuries have decimated both sides of the ball.

How to watch Sunday's Bears and 49ers game with betting lines and trends and radio information as Caleb Williams and Co. try ...

Williams’ wife, Sondra, announced on Instagram on Sunday, Dec. 1 that their son Trenton O'Brien Williams Jr. was stillborn on ...

The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...

Josh Allen expertly navigated snow-topped turf, finding the end zone in a multitude of fashions and even receiving credit for ...

Kyle Shanahan can no longer save the San Francisco 49ers. We have reached the month of December and quite the time in the NFL ...

The 49ers brass — Kyle Shanahan, John Lynch, and CEO Jed York chief among them — have not wavered on their commitment to ...

Sondra Williams, the wife of San Francisco 49ers tackle Trent Williams, said on social media that their son, Trenton, was ...

The 49ers opened the practice window for safety Talanoa Hufanga, who has missed the last seven games with a wrist injury.

The Bills are a Super Bowl contender and the 49ers somehow probably aren’t even a playoff team. That’s how Sunday night’s ...