Steve Borthwick has been forced into a drastic reshuffle of his Six Nations squad after Jamie George was ruled out of the opening two rounds, the former captain among four players to withdraw from the England squad.

England have suffered significant injury news ahead of the Six Nations with Jamie George ruled out of their opening fixtures against Ireland and France.Hooker George, who has been replaced by Maro Itoje as captain,

England head coach Steve Borthwick has been forced to call up five players after his Six Nations squad was rocked by injury on a damaging weekend of club rugby.

Borthwick has also been dealt a major setback with two scrum-halves missing the first week of training in the form of Alex Mitchell – who missed the Autumn Nations Series throug