Coming into the 2024 NFL season, it wouldn't have been out of the ordinary to find a Super Bowl prediction featuring the ...

SportsLine's model has simulated San Francisco vs. Buffalo on Sunday Night Football 10,000 times and revealed its SNF picks ...

The Game Matchups Preview series is dedicated to breaking down how the Buffalo Bills match up with their opponent in every ...

Following new injury reports, updated simulations reveal the best bet for 49ers vs. Bills on Sunday Night Football. Injury ...

The San Francisco 49ers battle the Buffalo Bills at 5:20 p.m. PDT on Sunday, Dec. 1 at Highmark  Stadium in Orchard Park, N.Y ...

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...

Providing the betting odds and our preview and prediction for the star-studded matchup between the San Francisco 49ers and ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

Buffalo Bills rookie wide receiver Keon Coleman has been designated as questionable for his team's Week 13 matchup with the ...

The San Francisco 49ers are bracing for snow ahead of Sunday's game in Buffalo, but new forecasts are painting a hopeful ...

In January, a lake-effect storm forced the NFL to push back the Bills' wild-card playoff home game against Pittsburgh by a ...