Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

The San Francisco 49ers on Wednesday began their week of practice as they gear up for what amounts to a season-ending stretch ...

Givens suffered a torn pec in the 49ers’ Week 13 loss to the Buffalo Bills. His injury-riddled season is over after only ...

What has to be done for the San Francisco 49ers to have a chance at the playoffs or at the very least, a winning season in ...

Former Wisconsin Badgers running back Isaac Guerendo is in line to serve as the San Francisco 49ers starting running back for ...

The San Francisco 49ers and fantasy football players who were relying on the NFC West team's running backs are probably all ...

San Francisco 49ers star running back Christian McCaffrey suffered a PCL injury and is expected to miss six weeks, head coach ...

Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling ...

San Francisco 49ers star running back Christian McCaffrey will not need surgery on his injured right knee but will miss the ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been ...

Watch highlights from the Week 13 matchup between the San Francisco 49ers and the Buffalo Bills during the 2024 NFL season.